Best Nootropic Supplements [2022] Top Nootropics That Work

Nootropics, also known as smart drugs, enhance memory, cognition and improve brain health.

Some nootropics are blends of herbal extracts, minerals, and vitamins. At the same time, others increase blood circulation to the

brain for better health. Nootropics supplements are in more demand than ever before; therefore, choosing the right supplements from various options available in the market is challenging.

We are here to assist you, so we have made a list of the best nootropics supplements available on the market.

33 Best Nootropic Supplements In 2021

Out of hundreds of nootropics supplements for improving brain health, we have formulated a list of the most influential and best nootropic supplements. This list is developed based on a variety of essential ranking factors.

Sane Vitaae Rejuvenates brain cells for clear thinking
Mind Lab Pro Fights against depression and anxiety
Nuzena Neuro Focus + Provides calms effect to the brain to reduce stress
NooBru Promotes mental and physical performance
Nootrogen Reduces mental fatigue and increases energy level
Ageless Brain Reduces age-related brain disorder
Onnit Alpha Brain Reduces the chances of memory loss
Hunter Focus Restores cognitive health
Qualia Mind Boost mental clarity and focus
Mind Strengthen memory power
Brain Boost Increases self-confidence and gives mental clarity
NeuroActiv6 Balances neurotransmitters for enhanced brain health
Synapse XT Gives sharper mind
NooCube Brain Productivity Improves learning abilities
Mind &MoodPromotes better sleep and mood patterns
PureHealth Research Ageless Brain Improves overall health and wellness
Brain Essense Supports multi-tasking and problem-solving abilities
Neuro Fuel Targets memory retention
Cymbiotika Golden Mind Allows one to have better mental health
Elm & Rye Nootropics Supports mental energy
CogniBioticsIt opens all brain pathways
Brain C13 Supports cognitive and mental health
Amy Myers MD Neuro Live Optimizes brain power and memory retention
Opti Mind Treats stress and depression
NeuroReduces social anxiety and depression
Youthful Brain Treats age-related brain illness
Brain Pill Boost mental clarity and focus
Remind Solution Reduces the chances of memory loss
Oweli Neuro Boost mood and sleep quality
Memory Hack Treats memory loss problem
Pro Mind Complex Works immediately to boost mental health
Memo Defend Better blood flow for restoring brain cells
Memosurge Protects the mind from cognitive decline

Let’s get into the details of each nootropic supplement on our list!

SANE Vitaae


Sane Vitaae is one of the brain supplements on this list due to a variety of reasons. Unlike other nootropics, Vitaae contains antioxidants such as CoQ10 to tackle inflammation in the brain. Some of the benefits of SANE Vitaae are enhancing mental clarity, concentration, mood, and overall mental function.

The company claims that the supplement increases brain energy utilization by 13.6% and membrane turnover by 26%.

Ingredients Vitamin D, citicoline, acetyl L-carnitine, omega 3 fatty acids, folate, and CoQ10
Key Highlights
  • Increases mental energy and enhances mental performance
  • Highly effective to optimize brain health
  • Improves significant mental and physical performance
  • Enhances cognitive health
  • Other Perks
  • 365 days money-back guarantee
  • A doctor recommends its brainpower
  • Price $47

    Mind Lab Pro


    If you are a first-time user of nootropic supplements, Mind Lab Pro is the right choice. This supplement is expensive but includes 11 science-backed ingredients.

    The NutriGenesis vitamins maximize the bioavailability and absorption of other nutrients, thus making the supplement more powerful. Mind Lab Pro is an internet top-rated brain supplement as it has third-party lab-tested ingredients and neuroscientists in the medical advisory board.

    Ingredients Vitamin B6, Vitamin B9, Vitamin B12, Citicoline, Bacopa monnieri, Organic lion’s mane mushroom, Phosphatidylserine, and N-acetyl L-tyrosine.
    Key Highlights
  • Enhances brain power for proper functioning
  • Reduces stress and anxiety-related symptoms
  • Improve cognitive function
  • Ensures better brain cells growth
  • Other Perks
  • 100% Money-Back guarantee
  • Free shipping
  • Price $69

    Nuzena Neuro Focus +


    Nuzena Neuro Focus+ is one of the most cost-effective brain supplements on this list. It is a great cognitive enhancer that ensures the person does not face any cognitive decline and has better mental performance.

    The company claims that their nutritional supplement supports memory, focus, and cognitive function of the brain. Moreover, it is GMP certified and made in an FDA-approved facility.

    Ingredients Bacopa extract, DMAE, Niacin, Glutamic Acid and Magnesium
    Key Highlights
  • Enhances cognitive performance
  • Supports healthy brain function
  • Boosts brain energy for long term brain health
  • Reduces the chances of depression and anxiety
  • Other Perks
  • 180 days money-back guarantee
  • Natural ingredients are added
  • Price $30



    NooBru is a transparent supplement that mentions the list of active ingredients and their dosages to the customers. Some of the elements in NooBru have proven cognitive benefits and help in enhancing the immune system

    You can consume tasty NooBru powder by mixing it in any beverage of your choice. It has proven advantages in boosting immunity, improving focus, energy, cognition, and mental clarity.

    Ingredients Alpha GPC, Astragalus Membranaceus Extract, Ginger extract, Panax Ginseng, Caffeine Extract, Piperine, Zinc, Ashwagandha, Rhodiola Rosia, Taurine
    Key Highlights
  • Increases brain cell regeneration
  • Reduces inflammation and stress symptoms
  • Promotes mental processing speed
  • Improves mental acuity
  • Other Perks
  • 90 days money-back guarantee
  • Free shipping on orders of above $50
  • Price $55



    Nootrogen is an affordable formula than other nootropic supplements on our list. It has unique ingredients that you won’t see in other supplements.

    It is one of the best brain supplements that promotes mental function and has mind-boosting properties that allow one to have improved focus, motivation, clarity, cognition, energy, and decreased stress.

    Ingredients L-tyrosine, Magnesium, Vitamin B3, Amino acid, DMAE, Bacopa extract, Vitamin B12, Vitamin B5, Phosphatidylserine
    Key Highlights
  • Supports mental performance
  • Promotes healthy brain cells
  • Improves cognitive abilities
  • Offers better mental clarity and focus
  • Other Perks
  • 180 days money-back guarantee
  • USDA organic certified ingredients
  • Price $30

    Ageless Brain


    If you are tired of consuming ineffective nootropic supplements, Ageless Brain is the right pick for you. The Ageless Brain has a beneficial effect on improving cognition due to the essential ingredients added to this formula.

    The ageless brain is a known brain supplement that offers a sharper level of thinking and increases focus alertness without any adverse effects. The company claims that this nootropic supplement is best for you if you want a laser-like focus, crystal clear memory, and a sharp mind.

    Ingredients Camu camu, cat’s claw, bacopa monnieri, cinnamon, pau d-arco, cacao, dragon’s blood resin, guayusa
    Key Highlights
  • Reduces memory loss
  • Alleviates age-related slow cognitive decline
  • Improve brain function and physical energy
  • Enhances mental performance
  • Other Perks
  • 365 days money-back guarantee
  • 100% safe formula
  • Price $55

    Onnit Alpha Brain


    Onnit Alpha Brain, Joe Rogan, the owner, claims that this formula supports focus, memory, and cognition. Unlike most brain supplements on this list, the Onnit Alpha Brain formula wins the race among competitors, backed by research and clinical trials.

    Onnit Alpha brain contains natural ingredients which aid in enhancing brain chemicals for better physical and mental performance. The supplement is one of the best cognitive enhancers that offer an array of cognitive abilities.

    Ingredients L-Theanine, Oat straw extract, Phosphatidylserine, Cat’s claw extract, Alpha-GPC, Bacopa monnieri extract, Huperzia serrata extract, L-Leucine, Pterostilbene
    Key Highlights
  • Prevent cognitive decline
  • Enhance cognitive performance
  • Improve brain function by producing new brain cells
  • Enhances energy levels
  • Other Perks
  • 90 days money-back guarantee
  • Free shipping over $150
  • Price $35

    Hunter Focus


    Hunter Focus contains natural and high-quality ingredients for providing clear thinking. It is also famous for its attractive packaging and transparency.

    The company discloses all the dosages of ingredients which is a positive point of the supplement. Each serving (four capsules) includes safe and tested Bacopa monnieri, phosphatidylserine, and passionflower, a solution to mental fatigue.

    Ingredients Lion’s mane mushroom, Ashwagandha, Citicoline, Passionflower, Baccopa Monnieri, L-Theanine, Phosphatidylserine, Maritime pine bark extract, and Vitamin B12
    Key Highlights
  • Soothes and calms down the brain to reduce stress
  • Open all brain pathways for better brain functions
  • Focus on brain cell development
  • It brings happiness by eliminating depression symptoms
  • Other Perks
  • 100% money-back guarantee
  • Manufactured in the USA
  • Price $60

    Qualia Mind


    Qualia Mind from Neurohacker Collective is a well-known nootropic supplement that contains 28 essential ingredients to improve focus, energy, memory, and brain health. The company offers four nootropic supplements: Qualia Mind Essentials, Qualia Focus, Qualia Mind caffeine-free, and Qualia brand. Every brain formula of the brand ensures the user experiences better brain function with numerous cognitive benefits.

    Qualia Mind is backed with thousands of positive reviews and five-star ratings.

    Ingredients Huperzia Serrata Leaf extract, Celastrus Paniculatus seed extract, Theobromine, Bacopa Monnieri leaf extract, Ginkgo biloba leaf extract, Velvet bean, Organic Coffeeberry
    Key Highlights
  • Improve mental performance
  • Boost nervous system for overall health and well being
  • Increases mental energy by ensuring better blood flow
  • Supports brain function and memory power
  • Other Perks
  • 100day money back guarantee
  • 100% safe supplement
  • Price $59

    Mind By Performance Lab


    The Mind nootropic supplement is from one of the best supplement-producing companies, Performance Lab. This effective formula can boost brain energy by 13.6%, support memory, and focus, enhance recovery, and improve motivation if taken daily.

    Performance Lab Mind contains active ingredients that boost blood flow in the body for more brainpower and physical performance. Also, the supplement includes antioxidants, minerals, vitamins, and other nutrients for improving cognitive brain function.

    Ingredients Cognizin citicoline, Sharp-PS phosphatidylserine, Ajipure L-Tyrosine, maritime pine park extract.
    Key Highlights
  • Alleviate mental fatigue
  • Nourish brain cells for enhanced mental energy
  • Promotes healthy nervous system
  • Support nerve growth factor for brain cell development
  • Other Perks
  • 30-day money-back guarantee
  • Vegan and keto-friendly nootropic supplement
  • Price $69

    Brain Boost


    Dr. Bill Raw has created a Brain Boost supplement for improving memory, supporting cognition, mental clarity, focus, immunity, mood, natural energy, and gut microbes.

    Brain Boost from Vital Plan contains natural nootropic ingredients for enhancing your health and wellness. The Brain Boost supplement is one of the most potent and transparent formulas as it discloses all relevant information regarding the formula.

    If you are looking for an excellent and doctor-formulated nootropic stack, then Brain boost is the excellent right choice for you.

    Ingredients Lion’s mane mushroom, cat’s claw, bacopa extract, Sensoril ashwagandha extract, and Ginkgo Biloba
    Key Highlights
  • Positive impact on memory retention
  • Alleviate mental fatigue
  • Increases mental energy by improving blood flow
  • Improve mental performance
  • Other Perks
  • 90-day money-back guarantee
  • Made under FDA approved centers
  • Price $48



    If you do not like to consume tablets, then Neuro Activ6 powdered formula is the right choice. You can take this nootropic supplement by mixing one scoop of powder in any beverage of your choice. Neuro Activ6 includes a range of superfoods that provide various mental benefits, so it is considered a great nootropic stack.

    The company claims that it can restore brain energy, prevent oxidative stress, increase BDNF levels, support healthy cortisol levels, and promote neural communications. The formula is effective in boosting brain function and protecting it from any age-related decline or damage.

    Ingredients Ashwagandha, Turmeric, Active B energy Complex, Citocoline, Coffee Fruit extract, fruit and vegetable blend, Organic Mediterranean berries
    Key Highlights
  • Soothes and calms the mind to reduce anxiety
  • Boost brain function for better memory power
  • Improves mental processing speed
  • Offers various cognitive functions
  • Other Perks
  • 60 days money-back guarantee
  • Manufactured under GMP practices
  • Price $46

    Synapse XT


    If you are an aged individual looking for a supplement to improve hearing and cognition, Synapse XT is a good solution for you. It contains plant-based extracts, minerals, herbs, vitamins, and other essential ingredients to support brain function and hearing. It is a great formula, and can be well used by patients with tinnitus and loss of memory.

    The Synapse XT manufacturing company claims that this nootropic stack can support senses and sounds, improve communication between cells, support memory, hearing, and cognitive function.

    Ingredients Hibiscus extract, Garlic, Hawthorn berry, amino acids, and Vitamins
    Key Highlights
  • Support ear and brain health
  • Restores brain chemicals for better mental health
  • Improve brain function
  • Provides clear thinking and problem-solving abilities
  • Other Perks
  • 60 days money-back guarantee
  • Free shipping all over the world
  • Price $69

    NooCube Brain Productivity


    NooCube Brain Productivity is a nutritional supplement by a neuroscientist. This supplement lacks caffeine but uses plant and herbal extracts to support cognition. It contains a composition of vitamins, amino acids, and other essential nutrients responsible for better brain health.

    NooCube Brain Productivity supplement is an expensive one in this list but delivers good value, high-quality ingredients in proper dosages to support the brain’s cognitive function.

    Ingredients Bacopa monnieri extract, L-tyrosine, cat’s claw concentrate, oat straw concentrate, L-theanine, Alpha GPC, marigold extract, resveratrol, and amino acids
    Key Highlights
  • Enhances cognitive functions
  • Reduces stress and age-related brain disorder
  • Used by patients of epilepsy
  • Elevate brain chemicals for proper brain function
  • Other Perks
  • 60 days money-back guarantee
  • Heavy discount on bulk orders
  • Price $60



    Neuro Fuel by Natural Stacks is the original formula for improving focus, concentration, and improved memory. Unlike other formulas, it contains large doses of a small number of ingredients making it an effective nootropic stack.

    This supplement is powered by blockchain technology and is the only open-source formula on this list that supports proper signals between brain cells. The supplement contains natural ingredients that have proven action on supporting neurotransmitters in the brain.

    Due to the company’s transparency, this is among the open-source nootropic stacks on our list.

    Ingredients Artichoke Extract, Forskolin, Acetyl-L-Carnitine, L-Phenylalanine, Vitamin B6, and amino acids
    Key Highlights
  • Boost learning thinking and problem-solving abilities
  • Improves memory power and focus
  • Better brain and mental health
  • Relaxes mind to treat depression
  • Other Perks
  • 100% Customer satisfaction
  • High quality and natural ingredients
  • Price $30

    Mind And Mood


    Mind and Mood is one of the supplements on this list formulated by a team of doctors. Dr. Joshua Levitt and Dr. Amanda Levitt created this formula by adding eight active ingredients responsible for increasing the blood flow and improving the development of brain cells for enhanced brain health.

    The company claims that the Mind And Mood formula improves your emotional health and manages stress, fatigue, brain fog, and anxiety.

    Ingredients Rhodiola, 5-HTP, GABA, saffron extract, L-theanine, passionflower extract, L-tyrosine, Amino acid, and Vitamin B6
    Key Highlights
  • Increases mental and physical energy level
  • Boost memory and focus
  • Ensures healthy mental and brain functioning
  • Eliminates stress and anxiety symptoms
  • Other Perks
  • Made in the United States
  • 90 days money-back guarantee
  • Price $57



    PureEssence Company discloses all ingredients added in the Brain Essence formula to know what you are consuming. It is a potent formula that creates outstanding mental support and a nervous system.

    You must take two tablets of this brain pill daily for optimum benefits such as improving focus, memory, clarity, energy, and mood.

    Ingredients Acetyl-L-Carnitine, Bacopa Monnieri, Organic Ashwagandha, Mucuna Pruriens, Schizandra Extract, Lion’s mane mushroom, Alpha Lipoic Acid, Phosphatidylserine, Gotu Kola Extract, Rhodiola, Fisetin Extract, Chinese Club Moss Extract
    Key Highlights
  • Promotes overall health and well being
  • Boost immune system
  • Supports mental clarity and focus alertness
  • Improve brain health
  • Other Perks
  • 100% money-back guarantee
  • Affordable nootropic stack
  • Price $30

    Pure Health Research Ageless Brain


    Dr. Holly Lucille created an Ageless Brain nutritional supplement, an effective and natural brain pill that supports brain health and reduces cognitive decline caused due to old age. The formula, reviewed in the AP News here, can decrease brain fog and anxiety, boost memory and cognitive function, and enhance focus.

    Ageless Brain is specially designed to target people who face aging brain symptoms and boosts cognitive health.

    Ingredients GABA, huperzine A, caffeine, L-Theanine, Amino acid, Niacin, Pyridoxine, L-Tyrosineand B vitamins
    Key Highlights
  • Promotes memory retention
  • Improves brain functioning
  • Eliminates stress hormones
  • Ensures proper mental function
  • Other Perks
  • 365 days money-back guarantee
  • Extra discount on the purchase of more than two bottles
  • Price $44

    Brain C-13


    Brain C-13 from zenith Labs is one of the top-rated formulas on this list as it is transparent in disclosing the ingredients and their dosages. This supplement contains herbal extracts that support mental awareness, targets memory retention, boost memory and energy level.

    A medical advisory board with expert doctors formulates Brain C-13, and you must take three capsules per serving or optimum benefits.

    Ingredients Ginkgo Biloba, bacopa monnieri, Rhodiola Rosea, DMAE, and turmeric, phosphatidylserine, huperzine A
    Key Highlights
  • Boost mental clarity and focus
  • Reduces memory loss chances
  • Better physical performance
  • Alleviates age-related cognitive disorder
  • Other Perks
  • 180 days money back guarantee
  • Clinically approved formula
  • Price $49

    Cymbiotika Golden Mind


    Cymbiotika Golden Mind is the only supplement available as a liquid tincture instead of powder or capsule. However, there are some unique ingredients that you won’t find in other formulas, such as buckthorn oil, Gotu kola extract, and a blend of 82 minerals. By consuming Golden Mind from Cymbiotika, you can reduce brain fog, nurture brain cell growth, and protect your brain.

    Ingredients Phosphatidylserine, green tea extract, bacopa powder extract, l-theanine, Rhodiola Rosea, ginseng, organic sea buckthorn oil, Gotu kola extract, amino acids, and lion’s mane powder extract
    Key Highlights
  • Strengthen brain’s performance
  • Increases focus and clarity
  • Supports memory recall
  • Improves brain productivity
  • Other Perks
  • 30 days money-back guarantee
  • Non-GMO nootropic stack
  • Price $50

    Elm And Rye Nootropics


    Elm and rye Nootropics supplement is the highest-priced formula on this list. Surprisingly it contains about 268mg of caffeine which equals about 2 to 3 cups of coffee.

    The supplement manufacturer is transparent about its ingredients and offers third-party lab testing to ensure the quality of this brain pill. The formula effectively enhances productivity, attention, stamina, memory, concentration, cognitive function, and focus.

    Ingredients Caffeine, bacopa, GABA, rhodiola rosea, Alpha GPC, phosphatidylserine, Huperzine A, and theanine
    Key Highlights
  • Reduces mental acuity
  • Increases mental health
  • Improves mental and physical energy
  • Boost cognitive function
  • Other Perks
  • Full money back guarantee
  • FDA approved ingredients(GRAS)
  • Price $85



    CogniBiotics is a nootropic supplement that acts on the digestive system for supporting brain health, mental clarity, memory, learning, and focus. The gut bacteria play an essential role in improving brain performance and cognition.

    Therefore CogniBiotics contains 17 nootropic and adaptogenic herbs that improve gut flora and thereby boost cognitive function, mood and decrease stress. Moreover, the supplement also has ten brain-friendly probiotic bacterial strains to support bacteria levels in your gut.

    Ingredients Cristaria plicata shell, Eclipta prostrate, Citrus reticulata, Paeonia Lactiflora, Schisandra Chinensis, Cristaria plicata shell, Prebiotic complex
    Key Highlights
  • Reduces blood clotting symptoms
  • Eliminates stress and anxiety
  • Promotes mental health
  • Ensures better immune system response
  • Other Perks
  • 365 days money back guarantee
  • 100% natural formula
  • Price $62

    Amy Myers MD NeuroLive


    NeuroLive is a doctor’s formulated supplement by Amy Myers MD. It is a brain booster formula containing seven high-profile micronutrients that supports brain and cognitive health in all ways.

    The ingredients, along with vitamin B6, fight against free radicals and oxidative damage. Also, it provides support to the brain cell membrane, supports memory and recall, enhances energy production and ideal methylation, supports blood circulation and healthy vasculature in the body.

    Ingredients Vitamin B6, Theanine, N-acetyl tyrosine, bacopa monnieri, mucuna pruriens, Ginkgo Biloba, Sharp PS phosphatidylserine
    Key Highlights
  • Enhances learning and problem-solving abilities
  • Supports mental function
  • Targets memory retention
  • Boost mental processing speed
  • Other Perks
  • 90 days refund policy
  • Free and discreet shipping
  • Price $49.97

    Neuro Gum


    NeuroGum is a functional gum for boosting energy, increasing calmness and focus of your mind. The company sells three different products: Neuro Gum for energy and focus, Neuro Gum for calm and clarity, and Neuro Gum for an ideal state.

    The gums and mints are available in cinnamon and peppermint flavors which many consumers like instead of swallowing a bitter capsule. Whether you are searching for an energy booster in the morning or any other time of day, you can take Neuro Gum or mint.

    Ingredients Sorbitol, Gum Base, L-theanine, Natural Flavors, Natural Caffeine, Calcium Stearate, Spirulina Flakes, Sucralose, Monk Fruit, Stevia, Pyridoxine
    Key Highlights
  • Enhances mental and cognitive health
  • Slows down age related symptoms of brain disorder
  • Reduces depression and stress level
  • Boost brain’s cell development
  • Other Perks
  • 30 days money back guarantee
  • Backed with five-star ratings
  • Price $21



    OptiMind is a nootropic supplement containing an active ingredient, Bacopa monnieri, with 55% bacosides. Bacosides are the vital chemicals found within this supplement to enhance its beneficial effects. Consuming OptiMind regularly gives you enhanced cognition, mental clarity, boosted energy, attention, and focus.

    Ingredients Phosphatidylserine, bacopa monnieri , Rhodiolarosea, maritime pine bark extract, taurine, vinpocetine, GABA, and caffeine
    Key Highlights
  • Eliminates stress and anxiety disorder
  • Optimize memory and focus alertness
  • Boost brain and cognitive health
  • It gives happiness as it soothes the brain
  • Other Perks
  • 60-day money-back guarantee
  • Price $39

    Youthful Brain


    The ingredients found in Youthful Brain, mentioned in the AP News here, include bacopa monnieri, vitamin B12, and Huperzine A; however, the dosages are lower than other supplements.

    This formula treats age-related memory loss and turbocharges your brain at the cellular level. It nourishes every part of the brain and helps to enjoy clarity and sharpness of the brain.

    Ingredients Bacopa monnieri, phosphatidylserine, rhodiola rosea, Ginkgo Biloba, and huperzine A
    Key Highlights
  • Works as an anti-aging formula
  • Supports overall health and wellness
  • Boost brain cells production
  • Enhances memory and learning abilities
  • Other Perks
  • 60 days money back guarantee
  • Recommended by doctor
  • Price $65

    Oweli Neuro


    Oweli Neuro Energy and Focus formula is a unique nootropic complex to enhance cognition, and mental performance, support memory, and learning enhance multitasking abilities, promote mood, fight stress, and promote zen-like focus and flow states.

    You must take two capsules daily for improved concentration and cognitive function.

    Ingredients B vitamins, n-acetyl-l-tyrosine, zinc, DMAE, bacopa monnieri, Huperzine A, phosphatidylserine, and inositol
    Key Highlights
  • Promotes better sleep and mood patterns
  • Improves concentration and memory
  • Best for treating depression and insomnia
  • Offers long term brain health
  • Other Perks
  • 90 days money back guarantee
  • FDA approved ingredients(GRAS)
  • Price $30

    ReMind Solution


    ReMind Solution is an expensive formula; thus, it gains a lower place on this list. It uses clinically proven ingredients to target anxiety, cognitive problems, stress, lack of focus, and other issues.

    The company offers discount offers on multiple bottles and is backed by a 60-days money-back guarantee.

    Ingredients St. John’s Wort, L-Glutamine, Phosphatidylserine, Bacopa Monnieri, Ginkgo Biloba, N-acetyl L-carnitine (NALC or NAC), vinpocetine, and Huperzine A
    Key Highlights
  • It gives clearer thinking and a sharper mind
  • Boost cognitive ability
  • Provides enhanced focus and learning abilities
  • Suitable option to fight high-stress levels
  • Other Perks
  • 60 days money back guarantee
  • No side effects
  • Price $69

    Brain Pill


    Brain Pill is marketed as an unfair advantage over the competition. It offers 13 nootropics to target mental fatigue, boost memory and focus, eliminate brain fog, improve cognitive function, and improve learning abilities. The company claims to use hefty dosages of ingredients; however, little information about the exact doses of ingredients in Brain Pill are disclosed.

    The formula was also recommended by Dr. Dave David and many other medical professionals, which is an advantage.

    Ingredients Citicoline, tyrosine, theanine, vitamin b12, Bioperine, Folic acid and Cognizin
    Key Highlights
  • It helps in avoiding distractions
  • Nourishes brain cells
  • Improves thinking ability
  • Ensures better working of the brain
  • Other Perks
  • 60 days money back guarantee
  • Free shipping
  • Price $69.95

    ProMind Complex


    Carl Henderson created the ProMind Complex formula with his vast years of experience. He claims that this formula is a perfect nootropic supplement. The formula only contains herbal ingredients and essential nutrients scientifically proven for improving mental health, cognitive abilities, and overall wellness.

    Ingredients Bacopa monnieri, vinpocetine, Huperzine A
    Key Highlights
  • Restores brain chemicals
  • Ensures there is healthy brain functioning
  • Boost cognitive abilities
  • Triggers memory retention
  • Other Perks
  • 60 days money back guarantee
  • Herbal ingredients
  • Price $69

    Memory Hack


    Memory Hack is a supplement created by Nutrition Hacks for cognitive function. It is priced at $69 higher than many other supplements, yet it includes ingredients in small doses.

    The company claims that the formula restores memory loss within six months and mainly targets people with memory disorders; however, it is unrealistic.

    Ingredients L-theanine Vitamin B3, Vitamin B6, and Vitamin B12 Ginkgo Biloba ​Phosphatidylserine
    Key Highlights
  • Promotes multi-tasking abilities
  • Boost brain functioning
  • Treats depression, epilepsy, bipolar disorder and more
  • Reduces the chances of memory loss
  • Other Perks
  • 60 days money back guarantee
  • Save money on subscription orders
  • Price $69



    MemoSurge is an innovative supplement that works in three steps. Firstly, it fires up neurotransmitters in the brain. Secondly, it repairs damaged brain cells and eliminates brain shrinkage. At last, the formula treats anxiety and insomnia.

    This formula is in the final list because it is not transparent in disclosing detailed ingredients, dosages, and concentrations. However, the company claims that MemoSurge improves general health and wellness.

    Ingredients Phosphatidylserine St. John’s Wort, N-Acetyl-L-Carnitine, Bacopa Monnieri extract, Vegetable magnesium stearate, Gelatin (bovine), Silicon dioxide, Microcrystalline cellulose.
    Key Highlights
  • Repairs damaged brain cells
  • Fights against depression and anxiety
  • Boost memory and mental clarity
  • Treats memory loss
  • Other Perks
  • 60 days money back guarantee
  • Made under GMP practices
  • Price $69

    Memo Defend


    Researcher Thomas Taylor made Memo Defend nootropic supplements. The supplement is a 620mg proprietary blend of herbs. However, detailed information about the dosages is not revealed. The most vital ingredient added in Memo Defend is vitamin B12, found in many other supplements.

    Ingredients Juniper berry, hibiscus, green tea extract, vitamin C, niacin
    Key Highlights
  • Strengthen mental health
  • Boost neurotransmitters
  • Reduces morning sickness and fatigue
  • Promotes better working of brain chemicals
  • Other Perks
  • Fast and free shipping
  • 90 days money back guarantee
  • Price $69

    How We Rank 33 Best Nootropic Supplements

    Due to the increasing demand for nootropic supplements, hundreds of formulas are available in the market, and all claim to provide benefits. Unfortunately, not all supplements are equally effective and safe to use.

    It becomes challenging to pick the best nootropic supplement, so we have made a list per the following essential ranking factors:

    Scientifically-Proven Ingredients

    Some ingredients have scientifically proven benefits of improving cognition and brain function as per research and clinical trials. After extensive research, it is established that plant and herbal extracts, minerals, and vitamins can boost brain function.

    Optimum Dosages

    A nootropic supplement can only be effective if it contains the effective dose of each ingredient. Many companies add science-proven ingredients to their product but not in optimum quantities. We choose those supplements that have the standard dosages of each component, as it increases the efficiency and safety of that product.

    Company Transparency And Reputation

    Some manufacturers have a long-standing record of producing high-quality and efficient formulas. At the same time, other companies are new in the market and do not disclose transparent labels.

    We include those companies that are transparent in disclosing ingredients, dosages, benefits and side effects of nootropic supplements. Also, companies with a good record of producing clinically effective supplements are on our list of best nootropic supplements.

    Doctor Formulated Products

    Doctors or the medical advisory board verifies not all supplements. The nootropic supplements that a doctor or nutritionist formulates are best. However, the companies that invest in their medical advisory board and include doctors are included in our list as it increases the credibility of the products.

    Lab Testing And Clinical Trials

    Most nootropic supplement-producing companies do not test their products in the lab, while some have reliable lab test reports. We prefer those supplements that are verified in the lab or clinically tested for efficiency and safety.

    Price Of Products

    We have listed the product from lower to higher price range. Whether you have to spend less or more, you will get the nootropic supplement in your price range. We consider those products as our top priority, which offers a good value of money.

    Money-Back Guarantee

    We rank the nootropic supplement-producing companies that offer a money-back guarantee. The effects of supplements may vary from individual to individual. Therefore, a money-back policy is beneficial for consumers and builds their trust.

    Honest Advertised Benefits

    Many manufacturers make big claims and market their products with unrealistic benefits. In contrast, other companies advertise actual benefits. We rank the nootropic supplements companies that are transparent and advertise what they offer.

    These were some of the ranking factors that we used for making our list of best nootropic supplements in 2021.

    Benefits Of Nootropic Supplements – According To Scientific Evidences

    Every nootropic supplement producing company makes many claims about the benefits of these supplements. However, do nootropic supplements work? Are there any scientific shreds of evidence supporting nootropic supplements?

    Nootropic supplements have gained popularity in the recent past. At present, you can find research and studies supporting the benefits of various ingredients added in nootropic supplements.

    Bacopa Monnieri, found in many nootropic supplements on our list, is one of the most studied ingredients. In a 2008 research, researchers found that the cognitive performance of older elders was increased by consuming 300mg of bacopa monnieri. Also, it reduced reaction time and improved memory in these adults. Many researchers concluded that bacosides in Bacopa monnieri are linked to its beneficial effects, such as improving memory and learning.

    Another ingredient Ginkgo Biloba is a well-known herb found in many nootropic supplements. It was used as a traditional medicine decades ago and is backed by multiple scientific studies. A 2001 study concluded that when researchers gave ginkgo Biloba and vinpocetine to participants for 14 days, it improved response times and memory.

    Moreover, Ashwagandha, used as traditional Indian medicine for centuries, is added in many nootropic medicines. It has been used for sleep, relaxation, stress management, and optimizing cardiovascular health. Research states that ashwagandha targets neurotoxins in the brain that obstruct cognition and memory. A study in 2016 concluded that Ashwagandha has nootropic and mind-protecting effects.

    Many of the above best nootropic supplements also contain Huperzine A. In a study in 1999 in china, researchers gave participants Huperzine A, and significant improvements were seen in memory, cognitive function, and symptoms of Alzheimer’s disease.

    L-theanine, another popular ingredient found in nootropic supplements, enhances the beneficial effects of caffeine while nullifying its adverse effects. A study concluded that consuming 50mg of L-theanine increased alpha brain wave activity. Similar research stated that L-theanine complemented the effects of caffeine while negating unwanted side effects such as anxiety.

    Additionally, clinical trials prove the efficiency of Onnit Alpha Brain nootropic supplement. In a study in 2016, researchers gave Onnit alpha brain supplement to 63 participants of 18 to 35 years of age for six weeks. These participants had improved verbal memory more than the placebo group. Some nootropics also use ginseng to enhance cognition. A study concluded that consuming 200 mg to 400mg ginseng enhances brain performance.

    Caffeine is the most popular nootropic agent, and many people consume caffeine regularly for nootropic effects. In a 2021 study, researchers found that caffeine, the world’s most widely consumed nootropic ingredient, alters the gray matter of the brain and brain electrical activity.

    Nootropic Supplement Dosages

    The dosages of nootropic supplements depend upon the ingredients and their concentration added in each nootropic supplement.

    Most nootropics available in tablets or capsules are taken once or twice daily. On the other hand, if the nootropic supplement is available in powder, one scoop of powder mixed with any beverage is consumed regularly for optimum effects.

    You must read the label of the supplement packaging for dosage instructions. However, some companies use proprietary labels, so you must consult your doctor before consuming any supplement.

    Nootropic Supplement Side Effects

    When taken in standard dosages, most people consuming nootropic supplements do not face any side effects; however, you can experience mild discomfort, nausea, indigestion, or headache.

    We recommend you follow the dosage instructions on the packaging of the nootropic supplement. If you are already on any medication or suffering from a comorbid condition, consult your physician before starting any supplement.

    Nootropic formula contains plant-based ingredients or herbal extracts which are safe to use. Some nootropics contain caffeine that may cause anxiety, jitters, nausea, and chest tightness at large doses.

    Frequently Asked Questions About Nootropic Supplements

    Q. What is a nootropic supplement?

    A: Any supplement that contains ingredients used to boost cognitive function is called a nootropic supplement.

    Q. What does a nootropic supplement do?

    A: Nootropics support brain performance in different ways. Some supplements boost memory and cognition, while others act on the electrical activity of the brain. Some also increase energy levels by working as a stimulant.

    Q. How can I take nootropics?

    A: Nootropic supplements are available more easily today than ever before. Nootropic supplements available in capsule and tablet form are taken once and twice per day, while you must consume one scoop of nootropic powder daily by mixing it with any beverage of your choice.

    Q. Which one is the best nootropic supplement available today?

    A: Any of the top-rated nootropic supplements on our list is the best to use in 2021.

    Q. Are nootropic supplements safe to consume?

    A: Many nootropics contain ingredients that are generally recognized as safe (GRAS) by the FDA. We recommend you follow the dosage instructions on the packaging of the nootropic supplement. If you are already consuming any medication or are suffering from a comorbid condition, you must consult your physician before starting any supplement.

    Q. What are the side effects of nootropic supplements?

    A: Most people consuming nootropic supplements do not face any side effects; however, you can experience mild discomfort, jitters, nausea, indigestion, or headache.

    Q. What benefits does a nootropic supplement offer?

    A: Some of the benefits of nootropic supplements are boosted memory, cognition, and brainpower. It also decreases stress levels and improves energy levels.

    Q. Who can benefit from a nootropic supplement?

    A: Athletes, college students, entrepreneurs’ parents, and whosoever need a cognitive boost can benefit from a nootropic supplement.

    Q. Are nootropic supplements legal to use?

    A: Most nootropic supplements contain ingredients that are generally recognized as safe by FDA. These are legal in many states.

    Q. Does a nootropic supplement contain natural ingredients?

    A: Most nootropic supplements contain natural ingredients such as herbal extracts, plant-based ingredients, vitamins, and minerals.

    Q. Does nootropic supplements cause addiction?

    A: Most nootropic supplements do not contain an additive ingredient. However, you can get addicted to anything.

    The Best 33 Nootropics Supplements In 2021 Final Thoughts

    Nootropic supplements are more popular than ever before. You can buy nootropic formulas at major online and offline retailers.

    There are varieties of nootropic supplements available today, but not all are equally effective and safe to use; therefore, we have made a list of the 33 best nootropic supplements that you can buy to optimize cognition, memory, and brain performance.

    This list is not an alternative to physician advice or an expert doctor. We recommend you consult a health professional to choose the best nootropic supplement for yourself. Always select the supplement that gives you more benefits with minimum side effects.

    RELATED:Best Adderall Alternatives: Top Supplements to Replace Adderall

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