Ranking the Top 7 Best Liver Cleanse Supplements That Work

Your liver is one of your body’s most vital organs. It’s commonly referred to as your body’s natural filter since it sifts through your blood, trapping toxins and other impurities before eliminating them. In addition, the liver is responsible for various vital processes, including blood cleansing, protein synthesis, hormone production, and digesting help. That is why it is critical to take care of your liver.

The liver is the largest organ in your body, around the size of a football. It is located on the right side of your abdomen, just below your rib cage. Because the liver is so huge and performs such a vital role, poor liver health can significantly influence your overall health. You may be thinking why I would need detox vitamins since this organ typically detoxifies the body. Your instincts are valid; you don’t need to take such types of medications, regardless of the specific benefits they promise to bring. However, if you have chronic liver disease or a health condition that includes the liver, your organ may benefit from some extra nutrients.

Many people use supplements daily to support liver health. An excellent liver detox supplement works on several levels of the organ. Some vitamins can help with inflammation. Others aid in the removal of pollutants from your body.

How We Ranked the Best Liver Supplements

All liver health pills promise to help the liver in a variety of ways. Some of them may help the liver to function correctly, while others do not. We utilized the following ranking methodologies to distinguish between the best and worst liver health supplements:

Proven HERBAL Ingredients

The inclusion of proven substances was the most crucial factor we looked for in a liver health supplement. Thousands of studies on the effects of vitamins, minerals, plants, and herbal extracts on liver health have been published. We chose pills that included this body of information in their formulation.

Clinically Effective Dosages

Surprisingly modest doses are seen in several liver health products. Some supplements include the correct components in incorrect quantities. Others contain doses that are far too low to have any effect on the body. We preferred liver health products that included clinically effective amounts.

Doctor Formulated

Some of the more reputable supplement firms have medical advisory boards composed of MDs, NDs, and other health specialists. These experts apply their medical knowledge to design the most beneficial liver health products. Doctors developed many of the top-rated liver health supplements mentioned above.

Advertised Benefits

Some companies sell their liver health products with outlandish health claims. They claim that their solution can cleanse the body and eradicate all poisonous waste. They say that you can drop 50 pounds by using their supplement, appear ten years younger, and treat liver disease. All of these assertions are implausible. We rated higher those liver health supplement firms that made legitimate health benefit claims in their advertisements and product documentation.

Manufacturer Reputation & Transparency

Some companies have a lengthy history of producing helpful supplements. Other manufactures are new and unproven. Some firms are open about the sources of their ingredients and the location of their manufacturing. Others are oddly evasive when it comes to this knowledge. We favored recognized, open-book manufacturers.

Price & Value

Some people are willing to pay $20 per month for a liver support supplement. Others are willing to invest more than $100. Our list contains supplements in various price ranges, but we stressed high value at all price points to ensure you were always getting top liver health ingredients for your money. The cheapest is not always the best deal when seeking an effective liver support supplement.

Ranking the Top 7 Best Liver Detox Supplements

The following seven supplements are the best liver pills for detoxification and cleansing benefits. Because of how many choices consumers have when shopping for the best liver supplements money that work, there will be a few other popular brand picks to comb through just in case neither of these top-rated ones are calling out to you loud enough:

Oweli Liver DetoxIt is a perfect combination of proven ingredients to detoxify the liver
Organifi Liver ResetThis supplement aid in better digestion and optimizes liver function
1MD LiverMDTo promote liver health and cleanse the liver, this is an ideal choice
Live Conscious LiverWellThis supplement is perfect to prevent various liver diseases
Amy Myers MD Liver SupportIt is a great formula to support liver health
Zenith Labs DetoxTo detoxify the liver and remove all toxic substances, Zenith Labs detox is a great addition in everyday diet
Gundry MD Complete Liver DetoxThis formula cleanses the liver and help to support liver health

The other options that may serve as worthy alternatives include:

Advanced Bionutritionals Liver SupportThis supplement is a perfect combination of antioxidants and anti inflammatory ingredients
Pure Health Research Liver SupportTo support liver health and optimal function of digestive tract, this is a perfect choice
ActivatedYou Morning CompleteIt boost energy and detoxify the body
Vita Post Liver Support PlusVita Post Liver support is an ideal choice to prevent liver diseases
Phytage Labs Urgent Liver 911To reduce the chances of liver damage and other liver diseases, Liver 911 must be added in daily routine

Here are our rankings of the top liver support supplements available online today, based on our research.

Oweli Liver Detox

Key Highlights
  • Support Optimal Liver function
  • Treat Liver Disorders
  • Reduce the risk factors of chronic hepatitis B
  • Manufactured under GMP facilities
  • Price$29.99
    Money-Back100 days

    Oweli is a reputable brand when it comes to liver detox products. Its powerful synergistic formulation contains potent natural ingredients with vitamins and minerals that support optimal liver health through gentle and gradual detoxification. The formula also helps support efficient lipid and fat metabolism that works against fat accumulation and inflammation.

    Oweli Liver Detox is scientifically formulated, incorporating natural ingredients that flush out toxins and help support optimal liver health naturally, completely free from additives, GMOs, and other harmful ingredients. It contains milk thistle as one of its key ingredients, a potent antioxidant that fights off free radicals that make the liver flush out toxins and protect other organs as it should. The premium ingredient list includes dandelion, chicory root, beetroot, artichoke extract, and yarrow, all of them are popular because of their anti-inflammatory properties. It is the best liver detox supplement.

    Organifi Liver Reset

    Key Highlights
  • Regenerate damaged liver cells
  • Provide many health benefits from a better immune system to better digestion
  • Support healthy liver function
  • Deliver nutrients for liver protection
  • Price$28
    Money-Back60 days

    Organifi’s Liver Reset is a well-known liver detox supplement. The manufacturer also uses organic components, including 300mg of organic Triphala, 300mg of organic dandelion root extract, and 250mg of organic milk thistle seed extract. Organifi Liver Reset contains liver-boosting superfoods which have all been used for generations to improve liver function. It is also one of the most affordable supplements on this list. All dosages and ingredient potency are transparent, making it simple to compare the formula to other liver health supplements marketed online.

    1MD LiverMD

    Key Highlights
  • This herbal supplement contains all antioxidant and anti-inflammatory ingredients
  • Reduce liver enzymes to support overall health
  • Boost immunity to reduce the risk of viral infections
  • Detoxify the liver and improve blood flow
  • Price$45
    Money-Back90 days

    1MD LiverMD may be the most accessible supplement on this list. It contains liver-healthy substances that have been professionally researched, such as milk thistle. The supplement also contains 800mg of NAC, 100mg of ALA, and high levels of essential vitamins and minerals such as zinc, vitamin E, and selenium. 1MD manufactures various dietary supplements that target different health and wellness goals, and 1MD’s LiverMD is one of the more popular ones today. 1MD LiverMD is one of the best liver support supplements available today, thanks to its high dosages and doctor-recommended mix. It is available for purchase online from significant merchants like Amazon and 1MD.com.

    Live Conscious LiverWell

    Key Highlights
  • Reduce the risk of liver diseases
  • Support healthy liver function
  • It is the best liver support supplement that contains proven ingredients
  • Promote overall health
  • Price$26
    Money-Back365 days

    Live Conscious promotes their popular LiverWell pill as a method to live a “happy life with a happy liver.” Using natural ingredients, the supplement strengthens the liver and works to improve metabolism. You can reportedly promote liver detoxification and protection, support healthy immune cell synthesis, and support a healthy metabolism by taking two capsules of LiverWell daily, among other benefits. Milk thistle extract, NAC, and ALA are among the constituents in LiverWell that have been related to liver health.

    Amy Myers MD Liver Support

    Key Highlights
  • Support healthy liver
  • Protect liver cells from further damage
  • Reduce the chances of liver transplant and boost overall health
  • Reduce the symptoms of hepatitis B and other liver diseases
  • Price$44.97
    Money-Back30 days

    Amy Myers MD creates various dietary supplements, out of all, there is a supplement called Liver Support, which combines substances that detoxify and optimize liver health. The supplement contains 200mg of NAC, a potent antioxidant that serves as a glutathione precursor. It also contains alpha-lipoic acid, which aids in the scavenging of free radicals. Amy Myers MD suggests taking one Liver Support capsule twice daily to provide your body with a potent blend of nutrients to assist detox.

    Zenith Labs Zenith Detox

    Key Highlights
  • Boost Joint Health
  • Improve energy levels and support skin health
  • Reduce certain liver enzymes that damage the liver
  • Support Liver detoxification
  • Price$20
    Money-Back180 days

    Zenith Detox from Zenith Labs promises to support liver function and good phase 1 and 2 detoxification. By taking the capsules daily, you may provide your body with the components required to maintain healthy liver function and scavenge and remove free radicals, among other advantages. According to the official website, the supplement can provide you with less joint aches, better physical stamina, a more youthful appearance, and increased confidence, among other health benefits not commonly associated with liver health products.

    Gundry MD Complete Liver Support

    Key Highlights
  • Support better immune health
  • Improve energy level and metabolism
  • Reduce the symptoms of allergic reactions
  • Promote overall liver health
  • Price$20
    Money-Back90 days

    The most economical liver health supplement on this list is Gundry MD Complete Liver Support. Complete Liver Support, which costs less than $20 per bottle, is touted as a “Swiss Army knife” for your liver. Complete Liver Support, according to Gundry MD, can aid increase nutrition absorption, support the immune system, support the metabolism, and support your body’s natural defense against environmental toxins, among other things. Complete Liver Support provides a high dose of a component not found in the other supplements on this list: 1,000mg of orange peel extract.

    Advanced Bionutritionals Advanced Liver Support

    Key Highlights
  • Promote brain and physical health
  • Cleanse the body and liver
  • Prevent the risk factors of cirrhosis
  • Support immunity
  • Price$44.95
    Money-Back90 days

    Advanced Bionutritionals manufactures an Advanced Liver Support supplement containing alpha-lipoic acid (ALA), phosphatidylcholine, milk thistle, selenium, among other things, glycyrrhizin and NAC. You can reportedly support your brain and liver health, support a healthy inflammation response, and protect your liver against oxidative stress by taking four capsules of Advanced Liver Support daily, among other benefits.

    PureHealth Research Liver Health Formula

    Key Highlights
  • Protect the body from liver disease
  • Support liver health
  • Reduce the risk of liver damage for hepatitis B patients
  • Detoxify liver and cleanse the body
  • Price$69
    Money-Back365 days

    PureHealth Research Liver Health Formula is a popular supplement created by a naturopathic doctor. According to the ND who produced Liver Health Formula, the pill will “recharge your body’s youth battery” while also providing you with “unlimited energy, a lean waistline, and keen thinking,” among other perks. Ginger, alfalfa, and beet are vital constituents in Liver Health Formula. Turmeric, dandelion, milk thistle, and artichoke leaf extract are among the other common liver-friendly substances found in other liver health products.

    ActivatedYou Morning Complete

    Key Highlights
  • Boost better digestion and gut health
  • Reduce oxidative stress
  • Support healthy blood pressure and blood sugar
  • Purify and cleanses the liver from toxic substances
  • Price$79
    Money-Back90 days

    The only product on our list that is not mainly touted as a liver health supplement is ActivatedYou Morning Complete. ActivatedYou Morning Complete, on the other hand, is an all-in-one daily health vitamin. Prebiotics, probiotics, green superfoods, fiber, and other components are included in the mix to help your health in various ways. ActivatedYou Morning Complete is described as a “strong daily wellness drink” by you. It is claimed that you can assist your body by consuming it daily to protect itself against oxidative stresses, promote good liver and cell function, and support healthy blood sugar, among other things.

    VitaPost Liver Support Plus

    Key Highlights
  • It is the best liver detox supplement
  • Regenerate damaged liver cells
  • Support overall health
  • Cleanse the liver and remove all toxins from the body
  • Price$28
    Money-Back100 days

    VitaPost Liver Support Plus is one of the more economical products. Like 1MD’s LiverMD, it is one of the few products on this list available at Walmart and other large merchants. Zinc, milk thistle extract, beet, artichoke extract, and celery seed are among the constituents found in each bottle of Liver Support Plus. Liver Support Plus by VitaPost contains more components – at lower doses – than the other formulations on this list. However, it may benefit liver health to a minor degree while providing excellent value at this price.

    Phytage Labs Urgent Liver 911

    Key Highlights
  • Prevent the chances of chronic liver disease
  • Suitable for liver detoxification
  • Support the healthy liver and metabolism
  • Boost immune health
  • Price$70
    Money-Back60 days

    Urgent Liver 911 is a Phytage Labs nutritional supplement. It contains nutrients such as milk thistle extract, beetroot, artichoke, dandelion, and celery seed, which help promote liver function in various ways. The dosages for Urgent Liver 911 are practically identical to those for Liver Support Plus. These chemicals are said to drain the fat-blocking your liver while also cleansing it and reversing damage, among other things. Urgent Liver 911 has a substantially lower value proposition at its price point than the other liver supplements on this list.

    Bonus Guide: The Non Alcoholic Fatty Liver Disease Solution


    Taking pills to support your liver isn’t the only way to help it. It is also about establishing good dietary and lifestyle practices by reducing alcohol consumption. Julissa Clay of Blue Heron Function News explains natural solutions for supporting liver health in various ways in this guide. Blue Heron Health News promotes the eBook as a “solution” to non-alcoholic fatty liver disease (NAFLD), a condition caused by lipid buildup in the liver. Julissa argues in The Non-Alcoholic Fatty Liver Disease Solution that fatty liver disease is “a decision” and “not a prison sentence.” Even if you have NAFLD, you can allegedly “get yourself well again” and “melt away that liver fat” by following her method.

    How to Naturally keep your liver healthy

    There is little research to say whether consuming vitamins will cleanse or protect your liver. Several lifestyle choices, however, have been demonstrated to benefit liver health. Here are a few pointers to help you keep your liver in good shape.

    Limit the fat in your diet

    A diet high in fried meals, sweets, and fast foods cause weight gain. Obesity and overweight raise the risk of nonalcoholic fatty liver disease. Maintaining a nutritious diet will result in a slimmer, healthier liver.

    Stay away from toxic substances

    Some insecticides, cleaning products, and aerosols contain compounds that can harm your liver when they are processed. If you must use these products, ensure that the room is well-ventilated. Don’t smoke. Smoking is harmful to the liver.

    Use caution when YOU drink alcohol

    Large amounts of beer, wine, or liquor harm liver cells and cause cirrhosis. Consume alcohol in moderation, no more than one to two glasses each day will help you to reduce the risk of alcoholic liver disease.

    Avoid chronic use of drugs

    Your liver must break down and eliminate every substance you consume. Steroids and inhalants, for example, might irreversibly harm this organ if used or abused regularly. Harmful or illegal drugs, such as heroin, can also injure the liver. They should be avoided at all costs.

    Don’t mix alcohol and medication

    Using alcohol and certain drugs at the same time can exacerbate liver damage. Before using any prescription drug, carefully read the directions. If the label warns that the combination is dangerous, don’t drink it.

    Popular supplement ingredients

    Many liver Detox supplements on the market include a blend of three natural ingredients:

    1. Milk thistle
    2. Artichoke leaf
    3. Dandelion root

    Let’s break down each element according to the studies.

    Milk thistle

    Milk thistle is a plant native to Europe transported to North America by early colonists. Milk thistle can currently be found throughout the eastern United States, California, and South America. The milky sap that flows out of the leaves when they are broken gives milk thistle its name. The seed of milk thistle may protect liver cells from harmful chemicals and medications. It also appears to have anti-inflammatory and antioxidant properties. Milk thistle is commonly used to treat liver problems such as chemical, alcohol, and chemotherapy-induced liver damage and Amanita phalloides (death cap) mushroom poisoning, jaundice, chronic inflammatory liver disease, cirrhosis of the liver, and chronic hepatitis.

    Artichoke leaf

    Antioxidant properties of artichoke leaf According to research, it may protect the liver. Animal studies indicate that it may aid in the regeneration of liver cells. Artichoke leaf reduced signs of liver damage in patients with nonalcoholic fatty liver disease in studies conducted in 2016 and 2018. The clinical benefits of artichoke leaf supplementation, on the other hand, are yet to be determined.

    Dandelion root

    Dandelion root has long been used to heal stomach and liver problems in traditional Chinese and Native American medicine. Herbalists now believe it can help treat various disorders, including acne, dermatitis, high cholesterol, heartburn, gastrointestinal issues, diabetes, and even cancer. Even though dandelion has been used to treat liver diseases, evidence of its advantages is limited. More research is required to discover whether it is safe and effective for this purpose.

    Other ingredients

    In addition to milk thistle plant, artichoke, and dandelion, liver support supplements differ by combining various other components. This can include items such as:

    Wild tam Mexican root

    Menopause symptoms, rheumatoid arthritis, diabetes, and muscle cramps are all potential medical uses for wild yam. Other names for wild yam include colic root, devil’s bones, rheumatism root, and China root.

    Yellow dock root extract

    Yellow dock is a laxative and tonic for pain and swelling (inflammation) of the nasal passages and respiratory tract. It is also employed in the treatment of bacterial infections and sexually transmitted illnesses. Yellow dock is also utilized in the treatment of intestinal diseases, fungal infections, and arthritis. Yellow dock is believed to benefit the digestive tract, liver, and skin and treat inflamed nasal passages.

    Hawthorn berry

    Hawthorn is used to treat heart and blood vessel problems such as congestive heart failure (CHF), chest discomfort, and irregular heartbeat. It may also be used to treat both low and high blood pressure, “artery stiffening” (atherosclerosis), and high cholesterol.

    Chanca Piedra

    Because of its antioxidant content, chanca piedra may boost liver function and protect the liver from cellular damage caused by free radicals – unstable chemicals that can cause damage when they accumulate in excessive amounts in your body. Human research demonstrating that these herbs work is yet lacking.


    Q: What exactly are liver supplements?

    A: Liver Support supplements are natural products that claim to help your liver’s health in various ways.

    Q: What exactly is the liver?

    A: The liver is a football-sized organ on the right side of your body, immediately below your ribcage. It removes toxins from your body and is essential for general health and wellness.

    Q: What are the benefits of liver supplements?

    A: Many liver supplements claim, among other things, to purify your liver and kidneys, protect your liver cells from inflammation, optimize your liver’s overall performance, and support your immune system.

    Q: How should I consume liver supplements?

    A: The majority of liver support supplements are in the form of capsules. You should take one or two capsules per day, as indicated. Other liver health supplements are in the shape of a powder, which you mix with water or your preferred beverage.

    Q: What is the finest liver supplement?

    A: Any top-ranked liver health pills on our list are one of the best liver detox supplements available anywhere.

    Q: What is the function of the liver?

    A: The liver is responsible for several vital activities in the body. It, among other things, processes nutrients absorbed through the intestines, regulates blood composition to balance proteins, fats, and sugars, destroys old red blood cells, produces essential blood-clotting chemicals, breaks down and metabolizes alcohol and medications, and produces critical proteins and cholesterol.

    Q: What is the source of liver damage?

    A: Diet and lifestyle variables, excessive drug or medicine use, excessive alcohol consumption, smoking, and other factors can lead to liver disease. Diseases such as hepatitis can also harm the liver.

    Q: Is liver illness inherited?

    A: Some liver illness is inherited, while others are caused by diet and lifestyle choices.

    Q: Aside from alcohol, what else causes liver damage?

    A: Although many people link alcohol with liver disease, you can also harm your liver by eating raw shellfish, taking too many drugs (such as acetaminophen), eating a bad diet, or being exposed to pollutants.

    Q: What are the symptoms of liver disease?

    A: Fatigue, bloating, gas, constipation, yellow skin or eyes, failure to lose weight, high blood pressure, mood and depression disorders, dark urine, excessive sweating, and poor appetite are all symptoms of liver disease. Many people who have liver disorders bruise quickly.

    Q: What is the best way to cleanse my liver?

    A: Some people cleanse or detoxify their liver for a few days or weeks by eating a balanced diet. Others augment their diet. Some people eliminate hazardous foods or practices. You might also drink raw vegetable juice, go on a juice cleanse, or exercise more frequently to assist your body to cleanse itself.

    Q: What are the signs and symptoms of liver disease?

    A: Fatigue or extreme tiredness, lack of enthusiasm, or itching are all symptoms of liver illness. As liver disease progresses, you may experience symptoms such as jaundice (yellowing of the eyes and skin), black urine, pale or light-colored feces, GI bleeding, mental disorientation and other cognitive difficulties, and fluid retention in the abdomen or belly.

    Q: How can I tell if I have liver disease?

    A: According to the University of Iowa, over half of those with underlying liver illness exhibit no symptoms. It can be challenging to identify. Consult your doctor about testing that can help you determine if you have liver disease.

    Q: Is it possible to reverse liver damage?

    A: The liver is the only organ in the body that can regenerate. In the case of other organs, such as the heart, your body repairs the damaged tissue with a scar. The liver, on the other hand, is capable of replacing damaged tissue with new cells. According to the University of Iowa, even significant liver damage caused by something like a Tylenol overdose, which killed 50 to 60% of liver cells, can be entirely restored after 30 days assuming no complications emerge.

    Q: Do you think I should take a liver supplement?

    A: Your doctor can advise you on whether a liver supplement is appropriate for you. Before using any supplement, consult your doctor, especially if you have liver disease or are taking medication.

    Q: What is the leading cause of liver disease in the United States?

    A: The most common cause of liver illness in the United States is alcoholism.

    Q: What is the largest organ in the body?

    A: Although the liver is the largest organ inside your body, the skin is the largest organ.

    Q: Is hepatitis considered a kind of liver disease?

    A: Hepatitis is a form of liver illness, yes. The term “hepatitis” literally means “liver inflammation.”

    Q: What exactly is cirrhosis?

    A: Cirrhosis is a type of chronic liver disease that is in its late stages. Cirrhosis is associated with scarring on the liver, even though it can typically repair itself (where your body has attempted to fix the liver without regenerating cells). Cirrhosis develops when scar tissue continues to build on the liver.

    Q: How do doctors assess the health of the liver?

    A: A liver function panel, also known as a hepatic function panel, is used by doctors to assess the liver’s health. It is a battery of blood tests performed simultaneously to detect liver inflammation (hepatitis), liver disease, or other liver damage and infections.

    Q: Should I do a liver cleanse regularly?

    A: There is no evidence that a liver cleanse can improve liver function. If your liver is in good health, it should be detoxifying your body already. A healthy diet and lifestyle choices, on the other hand, can help your liver’s natural detoxification ability in a variety of ways.

    Q: What is the healthiest diet for the liver?

    A: There is no such thing as a liver health diet. On the other hand, doctors frequently advocate the Mediterranean diet to persons with liver disease, emphasizing a high intake of fruits and vegetables. Doctors may also advise patients to consume more fiber-rich meals, whole-grain loaves of bread, and water. You should avoid foods that are heavy in saturated fat, sugar, and salt.

    Q: How effective are liver supplements?

    A: Some research has found that common constituents in liver health supplements, such as milk thistle, artichoke extract, and turmeric, can benefit liver function in various ways. The majority of these substances function by promoting liver inflammation.

    Q: Is it safe to take liver supplements?

    A: According to research, liver supplements are safe to take when taken in the authorized quantity. However, before taking any supplement, see your doctor, especially if you have liver disease or are taking medication.

    Q: Can vitamins wreak havoc on my liver?

    A: It is doubtful that taking a supplement in the prescribed dosages will affect your liver health. However, research reveals that herbal dietary supplements are responsible for 20% of liver damage in the United States.

    Q: What exactly is fatty liver?

    A: Fatty liver is a reversible condition defined by the accumulation of fat particles (triglycerides) in liver cells. A variety of diets, lifestyle choices, and hereditary factors can all contribute to it. Fatty liver has no risk of developing cirrhosis.

    Best Liver Health Supplements of 2022 Conclusion

    Liver Support supplements are promoted for their capacity to cleanse the liver of toxins and keep the liver in peak condition. So far, no scientific evidence has been shown to support these statements. Although some of the individual substances contained in liver support supplements may improve liver function, research shows that they are most beneficial to liver disease people. It is unknown whether these supplements can improve liver function in otherwise healthy people.

    If you don’t want to take a liver supplement, try taking the herbs individually. Milk thistle is the most helpful herb for your liver to take on its own. Several research studies have identified milk thistle as one of the top herbs for naturally detoxing your liver and digestive tract. Milk thistle, artichoke extract, zinc, and other substances have been shown in studies to promote liver health in various ways. These nutrients have been proven to assist the liver in cleansing itself and promoting liver function in other ways. If you’ve been thinking about incorporating a liver supplement into your diet, now is a perfect moment to do it. Any of the top-rated liver health supplements listed above could aid with liver health, detoxification, and cleansing in various ways.


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