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The game is played in Washington and 42 other states plus the District of Columbia and the U.S. Virgin Islands.
The drawing is scheduled Wednesday for 7:59 p.m. PST following a ticket sales cutoff of 7 p.m.
To win, a $2 ticket must match five numbers in any order plus the sixth specific Powerball number. The odds of winning are 1 in 175 million.
A single winner can take $400 million in a 29-year annuity or a lump-sum prize estimated at $227.8 million.
If nobody has a winning ticket, the jackpot rolls over and grows for Saturday’s lotto drawing. That could top a half-billion dollars.